反应详情

温度

38 °C

A mixture of 1.0 g of 5H-dibenz[b,e]azepine-6,11-dione in 50 ml of acetic acid is stirred while chlorine is bubbled into the reaction mixture until saturated. The temperature increases to 38° C. After standing, a precipitate forms and is filtered, washed with hexane and air dried to give 0.62 g of solid which is purified by chromatography to give the desired product as a solid, m.p. 289°-293° C.

1. customis bubbled into the reaction mixture until saturated
2. filtrationa precipitate forms and is filtered
3. washwashed with hexane and air
4. customdried