HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepine → N-[4-[(5,6-Dihydro-7H-pyrimido[5,4-d][1]benzazepin-7-yl)carbonyl]phenyl]-2,5-dichlorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepine | HCID 54396988 | — |
| Reactant | 4-[(2,5-Dichlorobenzoyl)amino]benzoyl chloride | HCID 54570079 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-[4-[(5,6-Dihydro-7H-pyrimido[5,4-d][1]benzazepin-7-yl)carbonyl]phenyl]-2,5-dichlorobenzamide | HCID 67625585 | — |
Reaction Steps
As described for Example 1, 5 mmol of 4-[(2,5-dichlorobenzoyl)amino]benzoyl chloride is reacted with 5 mmol of 5,6-dihydro-7H-pyrimido-[5,4-d] [1]benzazepine in pyridine to give the product as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05760031 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-9220b0b928fa45d7b9cdca9e2d7089c7 |
| Source note | uspto-grants-1998_06 |