M-Cresol → HCID 9995264, compound

HRID 962647Notes

Reaction equation

HRID 962647 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.Cl.[CH2:10]([N:17]1[CH2:22][CH2:21][C:20](=O)[CH:19]([C:24](OCC)=[O:25])[CH2:18]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:10]([N:17]1[CH2:22][CH2:21][C:20]2[C:5]3[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][C:4]=3[O:8][C:24](=[O:25])[C:19]=2[CH2:18]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 342M-CresolHCID 102623Ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride

Product 1

HCID 9995264HCID 9995264, compoundYield 60%

Procedure

Prepared by the procedure of Example 1 from 3-methylphenol and ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride. Yield 60%; mp 109°-111° C.

Sources & evidence

ORD record
ord-2082b19ac3b143a4b7163d447c0486d2
Source dataset
uspto-grants-1998_06
Patent number
US05760050

Reaction notes

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