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HRID 962680作成日:2026年10月25日

2-(4-Methylphenyl)propan-2-amine → N-[1-(4-Methylphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/962680

反応式

関与物質

役割名称HCID仕込み量
反応物2-(4-Methylphenyl)propan-2-amineHCID 584050—
反応物S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
生成物N-[1-(4-Methylphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 6764669588%

反応手順

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(4-methylphenyl)-1-methylethylamine (prepared as described in Preparation 10h) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 88%.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05760025
出典データセットuspto-grants-1998_06
ORD IDord-ca6a74caa39249d0a28300b15725a7b6
出典メモuspto-grants-1998_06