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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 962682Generated: October 31, 2026

S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate → N-[1-(4-Ethoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/962682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantS-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
Reactant2-(4-Ethoxyphenyl)propan-2-amineHCID 23009117—
ProductN-[1-(4-Ethoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 6764557591%

Reaction Steps

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(4-ethoxyphenyl)-1-methylethylamine (prepared as described in Preparation 10g) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 91%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05760025
Source datasetuspto-grants-1998_06
ORD IDord-88dbfcad63ee445f996591d73740dbe5
Source noteuspto-grants-1998_06