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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 962686Generated: October 26, 2026

4,4'-Dimethoxybenzhydrylamine → N-(4,4'-Dimethoxybenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamid

https://huagongshe.com/reaction/962686

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4'-DimethoxybenzhydrylamineHCID 350042—
ReactantS-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
ProductN-(4,4'-Dimethoxybenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamidHCID 1538027479%

Reaction Steps

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 4,4'-dimethoxybenzhydrylamine (prepared as described in Preparation 14) as starling materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 79%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05760025
Source datasetuspto-grants-1998_06
ORD IDord-29f0a16f0ca74c7ebd25ac26da0ea535
Source noteuspto-grants-1998_06