1-(4-Fluorophenyl)-1-methylethylamine → N-[1-(4-Fluorophenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide

Participants

Reaction Steps

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(4-fluorophenyl)-1-methylethylamine (prepared as described in Preparation 10f) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 82%.

Provenance & Evidence