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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 962688Generated: October 26, 2026

(4-Chlorophenyl)(phenyl)methanamine → N-(4-Chlorobenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/962688

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chlorophenyl)(phenyl)methanamineHCID 409810—
ReactantS-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
ProductN-(4-Chlorobenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 1538027670%

Reaction Steps

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 4-chlorobenzhydrylamine as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 70%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05760025
Source datasetuspto-grants-1998_06
ORD IDord-18980e123f1d493390844216679660cc
Source noteuspto-grants-1998_06