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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 962689Generated: October 26, 2026

1-(4-Methoxyphenyl)-1-phenylmethanamine → N-(4-Methoxybenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/962689

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Methoxyphenyl)-1-phenylmethanamineHCID 350041—
ReactantS-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
ProductN-(4-Methoxybenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 1538027882%

Reaction Steps

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 4-methoxybenzhydrylamine (prepared as described in Preparation 15) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 82%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05760025
Source datasetuspto-grants-1998_06
ORD IDord-8f2413f6196840a593b681a0997f7854
Source noteuspto-grants-1998_06