Methyl 4-ethoxybenzoate → 2-(4-Ethoxyphenyl)propan-2-amine

HRID 962705Notes

Reaction equation

HRID 962705 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1.[CH2:13](OC1C=CC(C(OC)=O)=CC=1)C>>[CH2:1]([O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:10])[CH3:11])=[CH:5][CH:4]=1)[CH3:13]

Participants

3

Reactant 2

HCID 90231Methyl 4-ethoxybenzoateHCID 110082782-(4-Methoxyphenyl)propan-2-amine

Product 1

HCID 230091172-(4-Ethoxyphenyl)propan-2-amineYield 60%

Procedure

Following a procedure similar to that described in Preparation 10a, but using methyl 4-ethoxybenzoate as a starting material, in a relative amount similar to that used in that Preparation, the title compound was obtained in a yield of 60%.

Workup

  1. customin a relative amount similar to that used in that Preparation

Sources & evidence

ORD record
ord-beaf32952e63409792e0f02b0fc18f46
Source dataset
uspto-grants-1998_06
Patent number
US05760025

Reaction notes

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