3H-Spiro(1-benzofuran-2,4'-piperidine) → HCID 54443956, compound

HRID 962732Notes

Reaction equation

HRID 962732 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4]2([CH2:10][C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[O:7]2)[CH2:3][CH2:2]1.BrCCCC[C:20]12[CH:30]=[CH:29][CH:28]=[CH:27][CH:21]1[C:22]([NH:24][C:25]2=[O:26])=[O:23]>>[N:1]1([CH2:2][CH2:3][CH2:4][CH2:5][C:27]2[CH:28]=[CH:29][CH:30]=[C:20]3[C:25]([NH:24][C:22](=[O:23])[C:21]=23)=[O:26])[CH2:6][CH2:5][C:4]2([CH2:10][C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[O:7]2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 127332303H-Spiro(1-benzofuran-2,4'-piperidine)HCID 19085843HCID 19085843, compound

Product 1

HCID 54443956HCID 54443956, compound

Procedure

From spiro[benzofuran-2(3H),4'-piperidine] prepared as described by R. C. Effland, et al. J. Heterocyclic Chem. 1981, 18, 81 1, and 2-(4-bromobutyl)-phthalimide using the procedure described for Example 15, Step 5 there was obtained a white solid: mp 255°-7° C.

Workup

  1. customwas obtained a white solid

Sources & evidence

ORD record
ord-093149fd7ac849dabf170faf34dcbb2c
Source dataset
uspto-grants-1998_06
Patent number
US05760054

Reaction notes

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