Hydrochloric Acid → HCID 19085851, compound

Participants

Reaction Steps

From 4-(6-methyl-2-oxo-3-benzoxazolinyl)-piperidine and 2-(4-bromobutyl)-1,1-dioxido-5-nitro-1,2-benzisothiazol-3(2H)-one using the procedure described for Example 15, Step 5 there was obtained a white solid:1H NMR, HCl salt, (400 MHz, CDCl3): 8.87 (d, J=2.0 Hz, 1H), 8.74 (d, J=2.18 Hz, 1H), 8.72 (d, J=1.8 Hz, 1H), 8.14 (d, J=8.4 Hz, 1H), 7.11 (d, J=6.54 Hz, 1H), 7.03 (s, 1H), 6.94 (d, J=8.06 Hz, 1H), 4.18 (m, 1H), 3.89 (t, J=7.39 Hz, 2H), 3.06 (d, J=10.07 Hz, 2H), 2.46 (m, 2H), 2.38 (s, 3H), 2.34 (m, 2H), 2.14 (t, J=11.5 Hz, 2H), 1.94 (m, 2H), 1.85 (d, J=11.4 Hz, 2H), 1.65 (m, 2H).

Provenance & Evidence