Imidazole → 1-[2-(1,3-Dioxolan-2-yl)ethyl]-1H-imidazole

HRID 962908Notes

Reaction equation

[O:1]1[CH2:5][CH2:4][O:3][CH2:2]1.[N:6]1[C:10]2C=CC=C[C:9]=2[NH:8][CH:7]=1.N1[CH:19]=[CH:18]N=C1>>[N:8]1[CH:9]=[CH:10][N:6]([CH2:18][CH2:19][CH:2]2[O:3][CH2:4][CH2:5][O:1]2)[CH:7]=1

Participants

Reactant 3

HCID 795Imidazole

HCID 5798Benzimidazole

HCID 125861,3-Dioxolane2×

Product 1

HCID 189134881-[2-(1,3-Dioxolan-2-yl)ethyl]-1H-imidazole

Procedure

NMR CDCl3 : 2.25 and 4.35: CH2 's of the ethyl; 3.85 to 4.00: CH2 's of the dioxolane; 4.87: CH dioxolane; 7.29-7.45-7.81: 4H benzimidazole; 7.92: H in position 2 of the imidazole.

Sources & evidence

ORD record: ord-cfbf0fb1e44d43c48124f06594c5a4ed
Source dataset: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05760233

Reaction notes

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