Sodium Hydroxide → HCID 19085267, compound

HRID 963060Notes

Reaction equation

[Cl:1][C:2]1[CH:40]=[CH:39][CH:38]=[CH:37][C:3]=1[C:4]([C:6]1[CH:10]=[C:9]([CH2:11][CH3:12])[S:8][C:7]=1[N:13]1[C:17]([CH2:18][NH:19][C:20]([C:22]2[N:23]([CH2:31][C:32]([O:34]CC)=[O:33])[C:24]3[C:29]([CH:30]=2)=[CH:28][CH:27]=[CH:26][CH:25]=3)=[O:21])=[N:16][N:15]=[N:14]1)=[O:5].[OH-].[Na+]>>[Cl:1][C:2]1[CH:40]=[CH:39][CH:38]=[CH:37][C:3]=1[C:4]([C:6]1[CH:10]=[C:9]([CH2:11][CH3:12])[S:8][C:7]=1[N:13]1[C:17]([CH2:18][NH:19][C:20]([C:22]2[N:23]([CH2:31][C:32]([OH:34])=[O:33])[C:24]3[C:29]([CH:30]=2)=[CH:28][CH:27]=[CH:26][CH:25]=3)=[O:21])=[N:16][N:15]=[N:14]1)=[O:5]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 19085130HCID 19085130, compound

Product 1

HCID 19085267HCID 19085267, compound

Procedure

Ethyl 2-(1-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-1,2,3,4-tetrazol-5-ylmethylcarbamoyl)indole-1-acetate is hydrolyzed using a 2M aqueous sodium hydroxide solution to give 2-(1-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-1,2,3,4-tetrazol-5-ylmethylcarbamoyl)indole-1-acetic acid.

Sources & evidence

ORD record: ord-72608af26d7f4c1dab2d3a8a12bcefa5
Source dataset: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05760032

Reaction notes

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