Benzenesulfonyl chloride, 3,4-dichloro- → HCID 19085294, compound

HRID 963065Notes

Reaction equation

HRID 963065 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9](Cl)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[NH2:13][CH2:14][C:15]1[N:19]([C:20]2[S:21][C:22]([CH2:34][CH3:35])=[CH:23][C:24]=2[C:25](=[O:33])[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=2[Cl:32])[C:18]([CH3:36])=[N:17][N:16]=1>>[Cl:32][C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][C:26]=1[C:25]([C:24]1[CH:23]=[C:22]([CH2:34][CH3:35])[S:21][C:20]=1[N:19]1[C:18]([CH3:36])=[N:17][N:16]=[C:15]1[CH2:14][NH:13][S:9]([C:4]1[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=1)(=[O:11])=[O:10])=[O:33]

Participants

3

Reactant 2

HCID 7383Benzenesulfonyl chloride, 3,4-dichloro-HCID 124343433-Aminomethyl-4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazole

Product 1

HCID 19085294HCID 19085294, compound

Procedure

3,4-Dichlorobenzenesulfonyl chloride and 3-aminomethyl-4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazole are reacted, and treated in the same manner as in Example 48 to give N-(4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-ylmethyl)-3,4-dichlorobenzenesulfonamide.

Workup

  1. additiontreated in the same manner as in Example 48

Sources & evidence

ORD record
ord-aba14572ae2042a8972e88daa151adcd
Source dataset
uspto-grants-1998_06
Patent number
US05760032

Reaction notes

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