HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 5-Ethoxymethylene-3-methyl-4-oxo-thiazolidine-2-thione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Thiazolidinone, 3-methyl-2-thioxo- | HCID 72900 | — |
| Solvent | Ethylorthoformate | HCID 53630039 | — |
| Product | 5-Ethoxymethylene-3-methyl-4-oxo-thiazolidine-2-thione | HCID 247101 | — |
Reaction Steps
3-Methyl-4-oxo-thiazolidine-2-thione (403 g) and ethyl orthoformate (1370 ml) were added to acetic anhydride (775 ml), and the mixture was refluxed for 6 hours. The mixture was allowed to stand, and the resulting crystals were collected by filtration and washed with diisopropyl ether to give 342 g of 5-ethoxymethylene-3-methyl-4-oxo-thiazolidine-2-thione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05760032 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-8a0e850c286743f58e512debd432ad5f |
| Source note | uspto-grants-1998_06 |