1H-indole-2-carbonyl Chloride → HCID 86752704, compound

HRID 963075Notes

Reaction equation

HRID 963075 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10](Cl)=[O:11].[NH2:13][CH2:14][C:15]1[N:19]([C:20]2[S:21][C:22]([CH2:34][C:35]([O:37][CH3:38])=[O:36])=[CH:23][C:24]=2[C:25](=[O:33])[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=2[Cl:32])[C:18]([CH3:39])=[N:17][N:16]=1>>[Cl:32][C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][C:26]=1[C:25]([C:24]1[CH:23]=[C:22]([CH2:34][C:35]([O:37][CH3:38])=[O:36])[S:21][C:20]=1[N:19]1[C:18]([CH3:39])=[N:17][N:16]=[C:15]1[CH2:14][NH:13][C:10]([C:2]1[NH:1][C:9]2[C:4]([CH:3]=1)=[CH:5][CH:6]=[CH:7][CH:8]=2)=[O:11])=[O:33]

Participants

3

Reactant 2

HCID 118162081H-indole-2-carbonyl ChlorideHCID 86752703HCID 86752703, compound

Product 1

HCID 86752704HCID 86752704, compound

Procedure

Indole-2-carbonyl chloride and methyl (2-(3-aminomethyl-5-methyl[1,2,4]triazol-4-yl)-3-(2-chlorobenzoyl)thiophen-5-yl)acetate are reacted to give methyl (3-(2-chlorobenzoyl)-2-(3-(2-indolecarbonylaminomethyl)-5-methyl[1,2,4]triazol-4-yl)thiophen-5-yl)acetate.

Sources & evidence

ORD record
ord-55a1f612adb34ac2a2657f9ad1b1a023
Source dataset
uspto-grants-1998_06
Patent number
US05760032

Reaction notes

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