Chlorophenyl isocyanate → HCID 86752705, compound

HRID 963076Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]=[C:9]=[O:10].[NH2:11][CH2:12][C:13]1[N:17]([C:18]2[S:19][C:20]([CH2:32][C:33]([O:35][CH3:36])=[O:34])=[CH:21][C:22]=2[C:23](=[O:31])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[Cl:30])[C:16]([CH3:37])=[N:15][N:14]=1>>[Cl:30][C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=1[C:23]([C:22]1[CH:21]=[C:20]([CH2:32][C:33]([O:35][CH3:36])=[O:34])[S:19][C:18]=1[N:17]1[C:16]([CH3:37])=[N:15][N:14]=[C:13]1[CH2:12][NH:11][C:9]([NH:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])=[O:10])=[O:31]

Participants

Reactant 2

HCID 76833Chlorophenyl isocyanate

HCID 86752703HCID 86752703, compound

Product 1

HCID 86752705HCID 86752705, compound

Procedure

2-Chlorophenyl isocyanate and methyl (2-(3-aminomethyl-5-methyl[1,2,4]triazol-4-yl)-3-(2-chlorobenzoyl)thiophen-5-yl)acetate are reacted to give methyl (3-(2-chlorobenzoyl)-2-(3-(3-(2-chlorophenyl)ureidomethyl)-5-methyl[1,2,4]triazol-4-yl)thiophen-5-yl)acetate.

Sources & evidence

ORD record: ord-bc9f3fe620f9467bb09619636e4dc1f9
Source dataset: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05760032

Reaction notes

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