HCID 11493075, compound → 1-(2-Deoxypentofuranosyl)-4-hydroxy-5-pentylpyrimidin-2(1H)-one

Participants

Reaction Steps

To a solution of 1.03 g (3.50 mmol) of 5-(1-pentynyl)-2'-deoxyuridine in 25 mL of MeOH was added a catalytic amount of 10% Pd on charcoal. The mixture was hydrogenated under 300 psi of H2 for 14 h at room temperature. The mixture was filtered through Celite and concentrated, affording a quantitative yield of product.

Provenance & Evidence