HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citric Acid → Guaifenesin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | D-(-)-Fructose | HCID 5984 | — |
| Reactant | Trisodium citrate | HCID 6224 | — |
| Product | Guaifenesin | HCID 3516 | — |
Reaction Steps
The maltitol was similarly admixed with Phase F to form Phase G to which the ammonium glycyrrhizinate was added with another about 5 minutes mixing time being used. The flavors and colorants were then admixed, with a mixing time of about 5 minutes, followed by addition of a sufficient amount of liquid fructose to make the desired volume and mixing to homogeneity. The pH value was thereafter adjusted to be between 4 and 5 using a citric acid or sodium citrate solution. This composition provides 100 mg of guaifenesin per 5 mL (teaspoon).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763449 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-66703a0f2bae41ba8bce66d2de9beb88 |
| Source note | uspto-grants-1998_06 |