2-Bromobenzenethiol → Ethyl 4-(2-bromophenylthio)but-2-enoate

HRID 963215Notes

Reaction equation

HRID 963215 reaction equation
BrC1C=CC=CC=1O[CH2:9][CH:10]=[CH:11][C:12]([O:14][CH2:15][CH3:16])=[O:13].[Br:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[SH:24].BrC/C=C/C(OCC)=O>>[Br:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[S:24][CH2:9][CH:10]=[CH:11][C:12]([O:14][CH2:15][CH3:16])=[O:13]

Participants

4

Reactant 3

HCID 805982-BromobenzenethiolHCID 5373944Ethyl (E)-4-bromobut-2-enoateHCID 54124865Ethyl 4-(2-bromophenyloxy)but-2-enoate

Product 1

HCID 54321606Ethyl 4-(2-bromophenylthio)but-2-enoate

Procedure

The title compound was prepared (26.1 g, 82%) in a manner analogous to the preparation of ethyl 4-(2-bromophenyloxy)but-2-enoate (Example 5) by the reaction of 2-bromothiophenol with ethyl 4-bromocrotonate.

Sources & evidence

ORD record
ord-a3c446c2fab14eff954cc2b96cdc76d1
Source dataset
uspto-grants-1998_06
Patent number
US05763444

Reaction notes

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