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p-Toluenesulfonate → 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | p-Toluenesulfonate | HCID 85570 | — |
| 反応物 | 1-[2-(2,3-Dihydro-benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride | HCID 19081436 | — |
| 反応物 | 1-(3-Methoxy-2-pyridinyl)-3-methylpiperazine | HCID 19081481 | — |
| 生成物 | 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride | HCID 19081472 | — |
反応手順
The title compound was prepared (1.04 g, 70%, mp 189°-193° C.) in a manner analogous to the preparation of 1-[2-(2,3-dihydro-benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride (Example 7) by the reaction of 3-benzo[b]thienpropanol tosylate with 1-(3-methoxy-2-pyridinyl)-3-methylpiperazine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05763444 |
| 出典データセット | uspto-grants-1998_06 |
| ORD ID | ord-58e068b2f8624662a4bd5a5c6fd360d3 |
| 出典メモ | uspto-grants-1998_06 |