p-Toluenesulfonate → 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(5-methoxy-4-pyrimidinyl)-3-methylpiperazine hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	p-Toluenesulfonate	HCID 85570	—
Edukt	1-[3-(Benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride	HCID 19081472	—
Edukt	1-(5-Methoxy-4-pyrimidinyl)-2-methylpiperazine	HCID 19081474	—
Produkt	1-[3-(Benzo[b]thien-3-yl)propyl]-4-(5-methoxy-4-pyrimidinyl)-3-methylpiperazine hydrochloride	HCID 19081475	—

Reaktionsschritte

The title compound was prepared (0.44 g, 62%, mp 183°-186° C.) in a manner analogous to the preparation of 1-[3-(benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride (Example 41) by the reaction of 3-benzo[b]thienepropanol tosylate with 1-(5-methoxy-4-pyrimidinyl)-2-methylpiperazine.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05763444
Quelldatensatz	uspto-grants-1998_06
ORD ID	ord-10ae04690d7d494b90ac1545ed185d03
Quellennotiz	uspto-grants-1998_06