Pyridine → HCID 21845224, compound

HRID 963252Notes

Reaction equation

HRID 963252 reaction equation
N1C=CC=CC=1.CN(C1C=CC=CN=1)C.C1(P(Cl)Cl)C=CC=CC=1.C(OC[CH:31]1[CH2:38][N:37]([C:39]2[CH:44]=[CH:43][C:42]([O:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH3:57])=[CH:41][CH:40]=2)[CH2:36][CH:35](COCCCC)[O:34][P:33](=[O:70])([C:64]2[CH:69]=[CH:68][CH:67]=[CH:66][CH:65]=2)[O:32]1)CCC>ClCCl>[CH2:46]([O:45][C:42]1[CH:43]=[CH:44][C:39]([N:37]2[CH2:36][CH2:35][O:34][P:33](=[O:70])([C:64]3[CH:69]=[CH:68][CH:67]=[CH:66][CH:65]=3)[O:32][CH2:31][CH2:38]2)=[CH:40][CH:41]=1)[CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH3:57]

Participants

6

Reactant 4

HCID 1049PyridineHCID 12573Phenyl phosphorus dichlorideHCID 218852-DimethylaminopyridineHCID 86752773HCID 86752773, compound

Product 1

HCID 21845224HCID 21845224, compoundYield 21%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

It is prepared from 4-dodecyloxy-N,N-di(2-hydroxy)ethyl aniline (3.66 g, 10 mmol), pyridine (2 g, 25 mmol), dimethylaminopyridine (0.2 g) and phenylphosphonous dichloride (2.15 g, 11 mmol) in dichloromethane as described for compound 200 to obtain a white solid 1 g (21%).

Sources & evidence

ORD record
ord-b69c7d762ab94105b74c8f6a3b0684f5
Source dataset
uspto-grants-1998_06
Patent number
US05763144

Reaction notes

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