Pyridine → HCID 21845230, compound

HRID 963255Notes

Reaction equation

HRID 963255 reaction equation
CO[C:3]1[CH:29]=CC(N(OCC(O)C(CC)CCC)OCC(O)C(CC)CCC)=[C:5](CCC)[CH:4]=1.N1C=CC=[CH:35][CH:34]=1.CN([C:42]1[CH:47]=CC=CN=1)C.C1(P(Cl)Cl)C=CC=CC=1.[CH2:57]([O:61][CH2:62][CH:63]1[CH2:70][N:69]([C:71]2[CH:76]=[CH:75][C:74]([O:77][CH2:78][CH2:79][CH2:80][CH2:81][CH2:82][CH2:83][CH2:84][CH2:85][CH2:86][CH2:87][CH2:88][CH3:89])=[CH:73][CH:72]=2)[CH2:68][CH:67]([CH2:90][O:91][CH2:92][CH2:93][CH2:94][CH3:95])[O:66][P:65](=[O:102])([C:96]2[CH:101]=[CH:100][CH:99]=[CH:98][CH:97]=2)[O:64]1)[CH2:58][CH2:59][CH3:60]>ClCCl>[CH2:94]([CH:93]([CH2:29][CH2:3][CH2:4][CH3:5])[CH2:92][O:91][CH2:90][CH:67]1[CH2:68][N:69]([C:71]2[CH:76]=[CH:75][C:74]([O:77][CH2:78][CH2:79][CH2:80][CH2:81][CH2:82][CH2:83][CH2:84][CH2:85][CH2:86][CH2:87][CH2:88][CH3:89])=[CH:73][CH:72]=2)[CH2:70][CH:63]([CH2:62][O:61][CH2:57][CH:58]([CH2:42][CH3:47])[CH2:59][CH2:60][CH2:34][CH3:35])[O:64][P:65](=[O:102])([C:96]2[CH:97]=[CH:98][CH:99]=[CH:100][CH:101]=2)[O:66]1)[CH3:95]

Participants

7

Reactant 5

HCID 1049PyridineHCID 12573Phenyl phosphorus dichlorideHCID 218852-DimethylaminopyridineHCID 54386311HCID 54386311, compoundHCID 86752773HCID 86752773, compound

Product 1

HCID 21845230HCID 21845230, compoundYield 32%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

It is prepared from 4-methoxy-N,N-di(2-hydroxy-3-ethyl-hexyloxy)-propyl aniline (2 g, 4 mmol), pyridine (0,8 g, 10 mmol), dimethylaminopyridine (0.2 g) and phenylphosphonous dichloride (0.8 g, 4 mmol) in dichloromethane as described for compound 200 to obtain a pale yellow liquid 0.8 g (32%) and its isomer 0.85 g (34%, a pale yellow liquid).

Sources & evidence

ORD record
ord-637fddd4bbd94de7a88da06a90c4e694
Source dataset
uspto-grants-1998_06
Patent number
US05763144

Reaction notes

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