HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanecarbonyl chloride → HCID 9844404, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanecarbonyl chloride | HCID 75938 | — |
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | (R)-[1-Methyl-2-(4-thiophen-2-yl-1,2,3,6-tetrahydropyrid-1-yl)ethyl]-pyrid-2-yl-amine | HCID 18660712 | — |
| Product | HCID 9844404 | HCID 9844404 | 82.4% |
Reaction Steps
The title compound was prepared from (R)-[1-methyl-2-(4-thiophen-2-yl-3,6-dihydro-2H-pyrid-1-yl)-ethyl]-pyrid-2-yl-amine (2.4 g, 8 mmol) and cyclohexanecarbonyl chloride (1.173 g, 8 mmol) in the manner described in Example 5 above to yield 2.7 g of title compound as the dihydrochloride, m.p. 103°-6° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763460 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-644faf1ffa094b32b67523c8368be0b6 |
| Source note | uspto-grants-1998_06 |