HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 1-[4-Amino-5-chloro-2-(3,5-dimethoxybenzyloxy)phenyl]-5-dimethylaminopentan-1-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 19081830 | HCID 19081830 | — |
| Product | 1-[4-Amino-5-chloro-2-(3,5-dimethoxybenzyloxy)phenyl]-5-dimethylaminopentan-1-one hydrochloride | HCID 19081839 | — |
Reaction Steps
Proceeding as in Example 4, Step (c), but replacing l-(4-acetylamino-5-chloro-2-methoxyphenyl)-5-chloropentan-1-one with 1-[4-acetylamino-5-chloro-2-(3,5-dimethoxybenzyloxy)phenyl]-5-chloropentan-1-one and piperidine with dimethylamine, gave 1-[4-amino-5-chloro-2-(3,5-dimethoxybenzyloxy)phenyl]-5-dimethylaminopentan-1-one hydrochloride, m.p. 221°-224° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763458 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-36a9ca08af174af6a88b469310de047e |
| Source note | uspto-grants-1998_06 |