Acrylonitrile → 3-(3-Iodo-phenylamino)-propionitrile

Participants

Reaction Steps

13at) 4.38 g of 3-iodoaniline, 1.06 g of acrylonitrile and 0.5 g of copper-(II)acetate are mixed and held at 70° for 5 hrs. The mixture is chromatographed on silica gel with ethyl acetate/cyclohexane 1:4 and yields 2.01 g of 3-(3-iodo-phenylamino)-propionitrile as a brown oil. Yield: 37%. Mass spectrum: peak inter alia at m/e : 272 (M+, 50%), 232 (100%); 105 (35%).

Provenance & Evidence