Tributylstannane → HCID 12040714, compound

Participants

Reaction Conditions

Reaction Steps

The compound ethyl 4-iodo-2,2,5,5,6,6,7,7,8,8,8-undecafluorooctanoate prepared from Example 5 (99.2 g, 0.2 mol) was added dropwise into a well-stirred tributyltin hydride liquid (58.5 g, 0.201 mol). The reaction temperature was controlled at ~30° C. during the process. After addition was complete, the mixture was stirred at 50° C. for 2 hr. The product ethyl 2,2,5,5,6,6,7,7,8,8,8-undecafluorooctanoate (65.0 g, 88% yield) was isolated by distillation as a clear, colorless liquid having a boiling point of 38°-39° C. at 3 mmHg.

Provenance & Evidence