反应详情

A mixture of 3-chloro-4-nitrophenol (10 g, 0.058 mole), benzyl bromide (11.8 g, 0.069 mole), and potassium carbonate (16 g, 0.116 mole) in acetone is stirred, heated at reflux temperature for 17 hours, cooled and filtered. The filtrate is concentrated in vacuo to give a solid residue which is recrystallized from absolute ethanol to give the title compound, mp 82°-84.5° C., identified by elemental and NMR analyses.

1. temperatureheated
2. temperatureat reflux temperature for 17 hours
3. temperaturecooled
4. filtrationfiltered
5. concentrationThe filtrate is concentrated in vacuo
6. customto give a solid residue which
7. customis recrystallized from absolute ethanol