HRID963664

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1118

Sulfuric acid

H2O4S

HCID3772977

2,4-Dinitrophenylhydrazine

C6H6N4O4

结构：CC(C=O)n1nnc2ccc(Oc3cc(F)c(C(F)(F)F)c(Cl)c3)cc21

HCID86747948

未命名化合物

PRODUCTS

生成物

结构：CC(C=NNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])n1nnc2ccc(Oc3cc(F)c(C(F)(F)F)c(Cl)c3)cc21

HCID86752766

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

A solution of 6-[(2-chloro-α,α,α,6-tetrafluoro-p-tolyl) oxy]-α-methyl-1H-benzotriazol-1-acetaldehyde (0.0294 mole) in ethanol is added to a solution of 2,4-dinitrophenylhydrazine (7 g, 0.035 mole) and conc. H2SO4 (35 ml, 0.63 mole) in H2O at 50° C., allowed to come to room temperature and filtered. The solid filter cake is recrystallized from aqueous acetic acid and from ethanol to afford the title compound, mp 148°-149° C., identified by elemental and NMR analyses.

WORKUP

后处理

customto come to room temperature
filtrationfiltered
filtrationThe solid filter cake
customis recrystallized from aqueous acetic acid and from ethanol

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fab1c786a4544b2baf153d4d8f30da17
来源数据集: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05763615
来源说明: uspto-grants-1998_06

反应 SMILES

[Cl:1][C:2]1[CH:7]=[C:6]([O:8][C:9]2[CH:10]=[CH:11][C:12]3[N:16]=[N:15][N:14]([CH:17]([CH3:20])[CH:18]=O)[C:13]=3[CH:21]=2)[CH:5]=[C:4]([F:22])[C:3]=1[C:23]([F:26])([F:25])[F:24].[N+:27]([C:30]1[CH:35]=[C:34]([N+:36]([O-:38])=[O:37])[CH:33]=[CH:32][C:31]=1[NH:39][NH2:40])([O-:29])=[O:28].OS(O)(=O)=O>C(O)C.O>[N+:27]([C:30]1[CH:35]=[C:34]([N+:36]([O-:38])=[O:37])[CH:33]=[CH:32][C:31]=1[NH:39][N:40]=[CH:18][CH:17]([CH3:20])[N:14]1[C:13]2[CH:21]=[C:9]([O:8][C:6]3[CH:5]=[C:4]([F:22])[C:3]([C:23]([F:26])([F:25])[F:24])=[C:2]([Cl:1])[CH:7]=3)[CH:10]=[CH:11][C:12]=2[N:16]=[N:15]1)([O-:29])=[O:28]