Hydrochloric Acid → 2-(5-Methoxy-1,2,3,4-tetrahydro-1-naphthyl)ethanol

Participants

Reaction Conditions

Reaction Steps

A suspension of ethyl (5-methoxy-1,2,3,4-tetrahydro-1-naphthyl)acetate (1.02 g) and lithium aluminum hydride (0.20 g) in tetrahydrofuran (15 ml) was stirred at 0° C. for 2.5 hours. The solution was poured into cold 1N-hydrochloric acid, then the resulting mixture was filtered through the celite, and extracted with ethyl acetate. The extract was washed with brine, dried over sodium sulfate, and evaporated in vacuo to afford 2-(5-methoxy-1,2,3,4-tetrahydro-1-naphthyl)ethanol as a colorless oil (0.85 g).

Provenance & Evidence