HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → 2-(2-Nitrophenyl)ethoxycarbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 2-Nitrophenethyl alcohol | HCID 27054 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(2-Nitrophenyl)ethoxycarbonyl chloride | HCID 15289332 | 94% |
Reaction Steps
Phosgene was introduced into a solution of 2-(2-nitrophenyl)ethanol (5.2 g, 31 mmol) in THF (20 ml, dist. over CaH2) at room temperature under stirring. After 1.5 h, the excess phosgene and the solvent were removed by distillation in a high vacuum. 2-(2-nitrophenyl)ethoxycarbonyl chloride (6.69 g, 94%) was obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763599 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-6f998c33a39c4313bc6e0565c356246c |
| Source note | uspto-grants-1998_06 |