HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 1-(4-Ethoxyphenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 1-(4-Ethoxyphenyl)-1-(2-fluoro-2-(methoxycarbonyl)ethenyl)cyclopropane | HCID 54288369 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(4-Ethoxyphenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane | HCID 54201534 | 74% |
Reaction Steps
The method of Example 9 was repeated using 1-(4-ethoxyphenyl)-1-(2-fluoro-2-(methoxycarbonyl)ethenyl)-cyclopropane (Example 2) (2.3 g), diethyl ether (20 ml) and lithium aluminium hydride (0.55 g) to yield the title compound (1.51 g, 74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763700 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-9747fbd770df4763a64f6afccfa66214 |
| Source note | uspto-grants-1998_06 |