HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 1-(2-Fluoro-3-hydroxyprop-1-enyl)-1-(3,4-methylenedioxyphenyl)cyclopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 1-(2-Fluoro-2-(methoxycarbonyl)ethenyl)-1-(3,4-methylenedioxyphenyl)cyclopropane | HCID 53809022 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(2-Fluoro-3-hydroxyprop-1-enyl)-1-(3,4-methylenedioxyphenyl)cyclopropane | HCID 54109861 | 89% |
Reaction Steps
The method of Example 9 was repeated using 1-(2-Fluoro-2-(methoxy-carbonyl)ethenyl)-1-(3,4-methylene-dioxyphenyl)cyclopropane (Example 6) (0.98 g), diethyl ether (15 ml) and lithium aluminium hydride (0.37 g) to yield the title compound (0.78 g, 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763700 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-915fca8f9872402c8dfc5b359b151919 |
| Source note | uspto-grants-1998_06 |