HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 1-(2,4-Difluorophenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 1-(2,4-Difluorophenyl)-1-(2-fluoro-2(methoxycarbonyl)ethenyl)cyclopropane | HCID 54323022 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(2,4-Difluorophenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane | HCID 54231943 | 71% |
Reaction Steps
The method of Example 9 was repeated using 1-(2,4-difluorophenyl)-1-(2-fluoro-2(methoxycarbonyl)ethenyl)cyclopropane (Example 7) (0.37 g), diethyl ether (10 ml) and lithium aluminium hydride (0.14 g) to yield the title compound (0.23 g, 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763700 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-088c7641d24a433bb127bced46a99dd5 |
| Source note | uspto-grants-1998_06 |