HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 1-(4-Difluoromethoxyphenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 1-(4-Difluoromethoxyphenyl)-1-(2-fluoro-2(methoxycarbonyl)ethenyl)cyclopropane | HCID 53901416 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(4-Difluoromethoxyphenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane | HCID 54107958 | 90.7% |
Reaction Steps
The method of Example 9 was repeated using 1-(4-difluoromethoxyphenyl)-1-(2-fluoro-2(methoxycarbonyl)-ethenyl)cyclopropane (Example 8) (0.77 g), diethyl ether (10 ml) and lithium aluminium hydride (0.2 g) to yield the title compound (0.63 g, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763700 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-0a216a194cb94b9e97207e7802dfd30b |
| Source note | uspto-grants-1998_06 |