HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → H-(L)-Pal-NH2
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Boc-(L)-Pal-NH2 | HCID 54368651 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | H-(L)-Pal-NH2 | HCID 67671136 | — |
Reaction Steps
Suspend Boc-(L)-Pal-NH2 (0.98 g) in methylene chloride (15 mL) with light heating and add a solution of hydrochloric acid (4M, 10 mL) in dioxane. After 30 minutes evaporate methylene chloride and dioxane. Dissolve the solid in methanol, precipitate by addition of ether and filtrate to give H-(L)-Pal-NH2. 2HCl (0.86 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05766932 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-d6373623d39543ca934f731c9d5e46e1 |
| Source note | uspto-grants-1998_06 |