Hydrochloric Acid → HCID 131720713, compound

Participants

Reaction Steps

Suspend Boc-(L)-Chg-(L)-Pal-NH2 (1.27 g, 3.12 mmol) in methylene chloride (50 mL), and add chlorhydric acid (10 mL, 4M in dioxane). After 30 minutes, evaporate dioxane and methylene chloride, dissolve the solid in methanol and precipitate the product by addition of ether (200 mL) and filter to give H-(L)-Chg-(L)-Pal-NH2.2HCl (1.12 g, 95%).

Provenance & Evidence