反应详情

A mixture of 4-carbamoyl-1-(2,4-dinitrophenyl)pyridinium chloride (50 g, prepared in a similar manner to that described in Example 2), aniline (35 ml) and methanol (11) was stirred at ambient temperature for 48 hours. The resulting suspension was heated at 50° C. for 1 hour, then cooled and the solvent removed in vacuo. The solid residue was triturated with acetone (2×11) then collected by filtration to give 4-carbamoyl-1-phenylpyridinium chloride (33.24 g), mp 290°-292° C.

1. customprepared in a similar manner to that
2. temperatureThe resulting suspension was heated at 50° C. for 1 hour
3. temperaturecooled
4. customthe solvent removed in vacuo
5. customThe solid residue was triturated with acetone (2×11)
6. filtrationthen collected by filtration