Sodium borohydride → HCID 19079313, compound

HRID 964023Notes

Reaction equation

HRID 964023 reaction equation
[BH4-].[Na+].[C:3]([C:11]1[CH:12]=[C:13]2[O:19][C:18](=[O:20])[N:17]([CH3:21])[C:14]2=[N:15][CH:16]=1)(=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>CO>[C:4]1([CH:3]([C:11]2[CH:12]=[C:13]3[O:19][C:18](=[O:20])[N:17]([CH3:21])[C:14]3=[N:15][CH:16]=2)[OH:10])[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 9795011HCID 9795011, compound

Product 1

HCID 19079313HCID 19079313, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Add 42 mg (1.1 mmol) of sodium borohydride to a previously prepared solution of 254 mg (1 mmol) of 6-benzoyl-3-methyloxazolo[4,5-b]pyridin-2(3H)-one in 20 ml of anhydrous methanol. Concentrate the reaction mixture to dryness under reduced pressure after stirring for 5 hours at room temperature, then take up the residue in water and isolate by filtration the resulting product; the title product is obtained in a yield of 84%.

Workup

  1. concentrationConcentrate the reaction mixture to dryness under reduced pressure
  2. customisolate by filtration the resulting product

Sources & evidence

ORD record
ord-e6360b44591c4496ab7b4aa3abfc0e6c
Source dataset
uspto-grants-1998_06
Patent number
US05767128

Reaction notes

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