反应详情

1,3-Dipalmitoylglycerol (2.5 g, 4.39 mmol) and 1-chloroethyl chloroformate (1.26 g, 8.79 mmol) were dissolved in chloroform (50 ml). To this was added anhydrous pyridine dropwise. The reaction mixture was stirred at ambient temperature for 5 days, diluted with dichloromethane and extracted with 0.5N HCl solution. The organic layer was washed with a saturated sodium bicarbonate solution, washed again with water, dried over sodium sulphate and concentrated to dryness. The waxy residue was dried under reduced pressure and used without further purification.

1. extractionextracted with 0.5N HCl solution
2. washThe organic layer was washed with a saturated sodium bicarbonate solution
3. washwashed again with water
4. dry with materialdried over sodium sulphate
5. concentrationconcentrated to dryness
6. customThe waxy residue was dried under reduced pressure
7. customused without further purification