Cesium carbonate → HCID 86752790, compound

HRID 964373Notes

Reaction equation

HRID 964373 reaction equation
[C:1]([NH:4][C:5]1[C:6]([I:21])=[C:7]([C:11]([I:20])=[C:12]([NH:15][CH2:16][C:17](=[O:19])[CH3:18])[C:13]=1[I:14])[C:8]([OH:10])=[O:9])(=[O:3])[CH3:2].C(=O)([O-])[O-].[Cs+:26].[Cs+]>O>[C:1]([NH:4][C:5]1[C:6]([I:21])=[C:7]([C:11]([I:20])=[C:12]([NH:15][CH2:16][C:17](=[O:19])[CH3:18])[C:13]=1[I:14])[C:8]([O-:10])=[O:9])(=[O:3])[CH3:2].[Cs+:26]

Participants

4

Reactant 2

HCID 10796Cesium carbonateHCID 18539450HCID 18539450, compound

Product 1

HCID 86752790HCID 86752790, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Conditions

Temperature
50 °C

Procedure

A suspension of 3-acetylamino-5-(acetylmethylamino)-2,4,6-triiodobenzoic acid (50.0 g, 79.62 mmol) in water (170 ml) was stirred and heated to 50° C. Cesium carbonate (12.8 g, 39.81 mmol) in water (20 ml) was added dropwise to the suspension until pH 7 was reached. Water was removed under reduced pressure to give a residue which was washed twice with ethanol and dried at 60° C. for 7 days.

Workup

  1. customWater was removed under reduced pressure
  2. customto give a residue which
  3. washwas washed twice with ethanol
  4. customdried at 60° C. for 7 days

Sources & evidence

ORD record
ord-d70b9ff29c9f4527aef13c1c979af04e
Source dataset
uspto-grants-1998_06
Patent number
US05767299

Reaction notes

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