Sodium Azide → HCID 53970366, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 32.14 g of benzyl 2-benzyloxycarbonylamino-2-desoxy-6-O-(p-tolylsulfonyl)-α-D-glucopyranoside in 75 ml of dimethyl sulfoxide was treated at room temperature with 7.5 g of sodium azide and stirred at 90°C. for 3 hours. The mixture was then poured on to ice/water. Separated crystals were filtered off under suction, washed with water and dried. There was obtained benzyl 6-azido-2-benzyloxycarbonylamino-2,6-didesoxy-α-D-glucopyranoside, [α]+l 119.6° (c 0.5; dioxan), MS: mlz 428 ([M+H]+).

Provenance & Evidence