Ethyl Bromide → HCID 19080477, compound

Participants

Reaction Conditions

Reaction Steps

While stirring under nitrogen, 8.8 g (33 mmol) of ethyl bis(3-fluorophenyl)phosphinite are slowly added dropwise to a solution of 7.27 g (16.6 mmol) of 2,2'-bis(bromo-methyl)-1,1'-binaphthyl in 40 ml of o-xylene, which solution has been heated to 120° C., with ethyl bromide distilling off. After the end of the addition, the mixture is heated under reflux for a further two hours and is then cooled to 0° C. The solid is filtered off, washed with cold o-xylene and dried in vacuo. This gives 11.5 g (91 %) of colorless crystals having a melting point of 280°-284° C.

Provenance & Evidence