2,2'-Bis(bromomethyl)-1,1'-binaphthyl → HCID 19080476, compound

Participants

Reaction Conditions

Reaction Steps

While stirring under nitrogen, 10.70 g (0.04 mol) of ethyl bis(4-fluorophenyl)phosphinite are added dropwise to a solution of 8.80 g (0.02 mol) of 2,2'-bis(bromo-methyl)-1,1'-binaphthyl in 40 ml of o-xylene, which solution has been heated to 135° C. After the end of the addition, the mixture is heated under reflux for a further 1.5 hours. After cooling to room temperature, the precipitated crystals are filtered off with suction and washed with xylene. This gives 14.1 g (94 %) of colorless crystals having a melting point of 211°-214° C.

Provenance & Evidence