HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → 2,6-Dipropyl-4-vinylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | t-Butyldimethylsilyloxy-2,6-dipropyl-4-vinyl benzene | HCID 19080390 | — |
| Reactant | Diethylether ethylacetate | HCID 21584169 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,6-Dipropyl-4-vinylphenol | HCID 18400414 | — |
Reaction Steps
The title compound was prepared from t-butyldimethyl-silyloxy-2,6-dipropyl-4-vinylbenzene (Step B, Example 14) by treatment with tetrabutylammonium fluoride in THF for a few hours. It was poured into ether/ethyl acetate mixture and washed with brine. After removal of the solvent the crude product was purified by flash column chromatography using ethyl acetate/hexane as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05767310 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-58545c78ce21451da326644a9ef52454 |
| Source note | uspto-grants-1998_06 |