HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86748470, compound → HCID 86748469, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86748470 | HCID 86748470 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86748469 | HCID 86748469 | 53.1% |
Reaction Steps
A hydrogenation bottle is charged with 2-pyrindine-7-carboxylic acid, methyl ester (0.8 g, 4.57 mmol), 5% Pd on carbon (2.0 g, wet) and methanol (125 ml). The slurry is hydrogenated (40 psi) until hydrogen uptake stops. The reaction mixture is filtered through celite and then evaporated to dryness to provide the product (430 mg) in 53% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05770586 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-b2ad2dc0d4fc439baf8549b4eb55067d |
| Source note | uspto-grants-1998_06 |