2,8-Diacetylamino-1-tetralone → 2-Acetylamino-8-amino-5-methoxy-1-tetralone

HRID 964643Notes

Reaction equation

HRID 964643 reaction equation
[C:1]([NH:4][CH:5]1[CH2:14][CH2:13][C:12]2[C:7](=[C:8]([NH:17]C(=O)C)[CH:9]=[CH:10][C:11]=2[O:15][CH3:16])[C:6]1=[O:21])(=[O:3])[CH3:2].C(NC1CCC2C(=C(NC(=O)C)C=CC=2)C1=O)(=O)C>>[C:1]([NH:4][CH:5]1[CH2:14][CH2:13][C:12]2[C:7](=[C:8]([NH2:17])[CH:9]=[CH:10][C:11]=2[O:15][CH3:16])[C:6]1=[O:21])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 120472982,8-Diacetylamino-1-tetraloneHCID 867509572,8-Diacetylamino-5-methoxy-1-tetralone

Product 1

HCID 224494332-Acetylamino-8-amino-5-methoxy-1-tetralone

Procedure

The same procedure as in Example 1-(4) was carried out, except that 200 mg of the compound prepared in (2) above was used instead of 2,8-diacetylamino-1-tetralone. Upon the post-treatment in the same manner as in Example 1-(4), 130 mg of the title compound was obtained.

Sources & evidence

ORD record
ord-63430700d101461484f1ea7957a2ba72
Source dataset
uspto-grants-1998_06
Patent number
US05770605

Reaction notes

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