Acetone → HCID 86750958, compound

HRID 964646Notes

Reaction equation

HRID 964646 reaction equation
[C:1]([NH:4][CH:5]1[CH2:14][CH2:13][C:12]2[C:7](=[C:8]([O:19][CH3:20])[CH:9]=[CH:10][C:11]=2[NH:15][C:16](=[O:18])[CH3:17])[CH2:6]1)(=[O:3])[CH3:2].CC(C)=[O:23].S([O-])([O-])(=O)=O.[Mg+2].[Mn]([O-])(=O)(=O)=O.[K+]>O>[C:1]([NH:4][CH:5]1[CH2:6][C:7]2[C:12](=[C:11]([NH:15][C:16](=[O:18])[CH3:17])[CH:10]=[CH:9][C:8]=2[O:19][CH3:20])[C:13](=[O:23])[CH2:14]1)(=[O:3])[CH3:2]

Participants

6

Reactant 4

HCID 180AcetoneHCID 24083Sulfuric acid magnesium salt (1:1)HCID 516875Potassium PermanganateHCID 86750959HCID 86750959, compound

Product 1

HCID 86750958HCID 86750958, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

190 mg of the compound prepared in (3) above was suspended into a mixture of 16 ml of acetone and 4 ml of 15% aqueous solution of magnesium sulfate, and to the solution was added 543 mg of potassium permanganate, followed by stirring for 1.5 hours at room temperature. Afrer the addition of 150 ml of water, the reaction mixture was extracted withe chloroform. The extract was waxhed with saturated brine and dried over magnesium sulfate. After removal of the solvent, the residue was ctystallized in ethyl acetate and hexane to produce 124 mg of the title compound.

Workup

  1. extractionthe reaction mixture was extracted withe chloroform
  2. dry with materialdried over magnesium sulfate
  3. customAfter removal of the solvent

Sources & evidence

ORD record
ord-a36ad318a20144eaa13b47886e504276
Source dataset
uspto-grants-1998_06
Patent number
US05770605

Reaction notes

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